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Senior Scientist, Bioreactor Process Design (I or II based on experience)

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Job Id JOB ID-09328 Standort Redmond, Washington Date posted 09/27/2023 Category Research & Development

Just – Evotec Biologics’ Bioreactor Process Development group is seeking an enthusiastic and hardworking team member who is passionate about expanding worldwide access to biotherapeutics through the advancement of continuous bioprocessing technology and mammalian cell culture processes.  This person will join a fast-paced, collaborative, and multidisciplinary team to support bioreactor process development (perfusion and intensified fed-batch) at the bench and pilot scale for the advancement of low-cost biotherapeutics manufacturing.   This position will oversee bioreactor process development and will include clone screening, process optimization, technology transfer, and process characterization for continuous perfusion and intensified fed-batch processes as well as technology development to support end-to-end continuous bioprocessing. The successful candidate will be detail-oriented, self-motivated, and efficient in completing hands-on laboratory tasks, and experience with bioreactor equipment operation and maintenance, lab management, and organizing workspace and tasks is required.  The ideal candidate will have strong scientific group management and leadership skills as well as a proven track record of a deep understanding of mammalian cell culture and perfusion bioreactor development for the production of clinical and commercial therapeutic proteins.  Strong written and verbal communication skills are required, and experience in client and multi-site communication is preferred.  Experience with common software packages (such as Microsoft Office, Google Suite, etc.) is required.  Finally, the ideal candidate is curious, creative, engaged, and the type who works well independently and in teams while constantly looking for ways to advance scientific processes and improve technology.


  • Leading a diverse group of scientists encompassing all aspects of bioreactor process development, characterization, and validation as well as tech transfer to cGMP manufacturing for perfusion and intensified fed-batch processes.

  • Preparing and running bench-scale bioreactors and bioreactor-related equipment (controllers, pumps, autoclaves, etc.) including building and autoclaving bioreactor parts and assemblies as well as assisting with bench-scale bioreactor operations (daily sampling and analytics, cleaning and maintenance, inoculation activities, run preparation, and troubleshooting).

  • Serving as a functional area lead for platform or complex client early-stage (FIH) and late-stage Process Characterization (PC) projects as well as technology development projects.

  • Serving as a Project Team Lead within the process development organization to execute on client projects that involve multiple functional areas for platform, early-stage (FIH) projects.

  • Serving as an internal technical resource for cGMP manufacturing and Process Design, as well as a resource and subject matter expert for external clients and partners for cell culture and bioreactor processes (small scale models, process transfer, and scale up).

  • Communicating experimental plans and data to teams and clients clearly and effectively including communicating scientific information to a diverse set of audiences, including external clients, vendors, and technology development collaborators.

  • Independently designing, executing, and analyzing statistically designed experiments (DOE).

  • Documenting best practices and technical results in ELNs, SOPs, summary reports, etc.

  • Authoring SOPs, reports, and slides which summarize, organize, and interpret experiment results with review by appropriate team members.

  • Working with vendors and manufacturers in developing, ordering, and troubleshooting equipment prototypes.

  • Training, mentoring, and supervising staff and interns.

  • Driving technology development for process intensification and continuous manufacturing to reduce manufacturing costs and footprint through improvements in culture productivity, control of product quality, and data management.

  • Supporting the management of staff, capital resources, and planning within the department.

  • Potential for weekend work (5-day work week/ 2 days off) and being on-call for critical bioreactor runs.

  • Other tasks as assigned.

Required Qualifications

  • BS/MS in Engineering, Biochemistry, Biology, or related field with 10-12+ years of experience (12-15 yrs for Sr. Scientist II) or Ph.D. with 3-5+ years (6-9 years for Sr. Scientist II) of experience.

  • Expertise in bioreactor cell culture and perfusion technology development, transfer to cGMP manufacturing plants, and reviewing CMC sections of regulatory filings.

  • Experience with commercial process development, process characterization, and validation.

  • Expertise in design of experiments (DOE) and statistical analysis.

  • Experience in training, mentoring, and supervising team members as well as leading bioreactor development teams for external client projects and collaborations and internal technology development initiatives. 

  • Experience with high throughput cell culture technologies (e.g. HT assays, robotics such as Ambr systems, lab automation, or multi-omic data) is a plus.


  • Experience analyzing data in tools such as JMP, R, or Python.

  • General understanding of cell biology, fluid dynamics, and biotransport as well as knowledge in other functional areas (downstream purification and analytical sciences).

  • General understanding of circuits (grounding, power, signal, etc.).

  • Experience working in a cGMP or clean room setting (this job is non-GMP but knowledge of GMP is helpful for process/tech transfer activities).

  • Experience working in retail, service industry, or other environments that require physical work and positive attitude.

The base pay range for this position at commencement of employment is expected to be $93,000 to $131,000;  Base salary offered may vary depending on individual’s skills, experience and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision, short-term and long-term disability, company paid basic life insurance, 401k company match, flexible work, generous paid time off and paid holiday, wellness and transportation benefits.

Evotec (US) Inc. is an Equal Opportunity Employer.  All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.

What makes us unique 

  • rocket

    Our business model

    With Evotec’s Action Plan 2025 “The data-driven R&D Autobahn to Cures”, our goal is to stay competitive in the ever evolving life science industry. Together for medicines that matter.

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  • builb

    Our expertise

    Togehter, we are creators and turn imaginations into cures. With Evotec, a smart idea can unfold and mature, with the help of our high expertises and cutting-edge technologies.

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  • group

    Our team

    Our collaborative and trustful work environment enables solution-oriented discussions among colleagues. We inspire each other to great aspirations and know that, together, we’ll go further.

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Success Profile

Cultural fit and soft skills are important factors for success. Check out the traits we’re looking for:

Success Profile

Cultural fit and soft skills are important factors for success. Check out the traits we’re looking for:

  • Curiosity
  • Resilient
  • Creative mindset
  • Teamplayer
  • Forward-thinking
  • Adaptable


Our Data-driven Autobahn Towards Cures