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Sr. Associate Scientist, Purification

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Job Id JOB ID-09935 Standort Toulouse, France Date posted 12/21/2023 Category Biomanufacturing

Scientist Bioreactor Process Design (all genders)

Permanent contract

Just-Evotec Biologics is looking for a Scientist of Bioreactor Process Design to join a fast-paced, collaborative, and multidisciplinary team working on upstream process development (perfusion and intensified fed-batch) projects. In this role, you will participate in further developing and refining Just’s next-generation continuous bioprocessing platform, which we are currently running in our Seattle and Redmond manufacturing facilities at 500L and 1000L scale. Just-Evotec employees are driven by our mission: to expand access to therapeutics by substantially driving down the cost of goods through process technology development. This role is well-positioned to have a substantial impact on patients and the biotechnology industry.

This position will be part of a team to perform upstream process development for early and late-stage processes and will include process development, optimisation, characterization, and technology transfer for intensified, continuous processes. The successful candidate will be detail-oriented, self-motivated, efficient, curious, and work well in a team environment. Strong written and verbal communication skills, including the ability to communicate effectively over teleconferences and web-based meetings, are necessary.


Responsibilities:

  • Developing and/or assisting upstream processes for biotherapeutics manufacturing

  • Designing, executing, and analysing statistically designed experiments (DOE) either independently or with support from manager

  • Ensure accurate and complete documentation of lab activities and write appropriate technical reports for successful regulatory submission.

  • Ensure the upstream development (USP) labs and equipment is maintained under optimal working conditions and assume responsibility for specific instruments.

  • Contribute to investigations (e.g., deviations) as required to help identify the root cause and propose and implement appropriate corrective actions. 

  • Carry out Development/Characterisation/optimisation experiments, accurately document results, and produce experimental reports.

  • Support tech transfer with manufacturing organizations (internal and external)

  • Responsible for own professional attitude and for sharing knowledge for the benefit of others or on demand.

  • Author, amend and review operating documents, such as SOPs, guidelines, and data records. Willing to take on additional activities.

  • Documenting best practices and technical results in ELNs, SOPs, summary reports, etc.

  • Working with vendors and manufacturers

  • Assisting with bench-scale bioreactor operations including run preparation, bioreactor assembly, autoclave, inoculation, daily sampling and analytics, troubleshooting, cleaning, and maintenance

  • Potential for weekend work (5-day work week/ 2 consecutive days off)

FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.

ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.