Scientific Director – Discovery and Protein Science
Just – Evotec Biologics is seekinga highly motivated and creative antibody discovery and protein science director that desires a significant opportunity to improve worldwide access to biotherapeutics. The position will lead a group of scientists in expanding and utilizingan AI-driven platform of Fab on phage and VHH on yeast display platforms, the development of methods and procedures for fast vector and antigen creation, and highly parallel research therapeutic production methods.This role leads the design and implementation of advanced antibody-based biotherapeutic discovery and translation to lead therapeutics,maintaining updated understanding of discovery platforms, even those outside of those implemented at Just. The role requires the ability to recruit for and lead functional areas in a discovery organization including library design, DNA synthesis, library creation methods such as phage, yeast, and CHO platforms, antigen design and production, high-throughput screening and activity assays, NGS methods, therapeutic modality design, laboratory automation, and high-throughput and larger scale lead production.The successful candidate must also possessstrong communication and collaboration skills, a desire to learn new scientific concepts and domains, and an ability to work directly with scientific staff across multiple disciplines.
Responsibilities:
Lead protein science functions such as DNA synthesis, vector creation, and protein production
Expand and utilize multiple mAb and VHH based discovery libraries with supporting functions required to drive lead biotherapeutic development
Drive automation and ultra-high throughput methods for active programs and data generation
Lead budget creation and track costs associated with building and running a discovery organization
Hire, train, and organize necessary staff, as well as manage existing staff
Lead and mentor staff to work innovatively and collaboratively
Engage with scientific leadership throughout the company to tailor methods to broader platform
Operate with a drive toward innovation across functions
Deep understanding of the technological challenges in biotherapeutics discovery, molecular design, process development, and manufacturing and provide input toward effortsto address these challenges
Excellent communication skills; comfort presenting findings and pitching business cases to technical, senior leadership and executive audiences
Education qualifications and other Requirements:
Ph.D. in a related scientific area
15+ years of relevant experience, 10+ years of team and project management experience
Strong drive toward innovation in areas of discovery platforms and application of discovery, including design and use of libraries for large-scale data generation driving machine-learning methods, generation of modalities for repeated use such as cell engagers and receptor-mediated relocation strategies, and methods for therapeutic translation toward manufacturing
Strong understanding of mAb and mAb-based structural biology to aid in modality designs and data generation to improve design methods
Possesses extensive leadership and mentoring capabilities, along with strong written and verbal communication skills
Able to present capabilities and results to targeted and general audiences and to publish as applicable
Viewed as a thought leader in the field
The base pay range for this position at commencement of employment is expected to be $190,000 to $220,000; Base salary offered may vary depending on individual’s skills, experience and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision, short-term and long-term disability, company paid basic life insurance, 401k company match, flexible work, generous paid time off and paid holiday, wellness and transportation benefits.
Evotec (US) Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.
What makes us unique
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Our business model
With Evotec’s Action Plan 2025 “The data-driven R&D Autobahn to Cures”, our goal is to stay competitive in the ever evolving life science industry. Together for medicines that matter.
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Our expertise
Togehter, we are creators and turn imaginations into cures. With Evotec, a smart idea can unfold and mature, with the help of our high expertises and cutting-edge technologies.
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Our team
Our collaborative and trustful work environment enables solution-oriented discussions among colleagues. We inspire each other to great aspirations and know that, together, we’ll go further.
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Success Profile
Cultural fit and soft skills are important factors for success. Check out the traits we’re looking for:
Success Profile
Cultural fit and soft skills are important factors for success. Check out the traits we’re looking for:
- Curiosity
- Resilient
- Creative mindset
- Teamplayer
- Forward-thinking
- Adaptable
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