ALTERNANCE - Cell Line Development (all genders)
ALTERNANCE dès Sept 2025
Toulouse
Mission principale : finaliser la mise en œuvre d'une plateforme de développement de lignées cellulaires, appelée J.CHO, et évaluer les possibilités d'optimisation.
Pour vous en dire plus...
Il sera nécessaire de mettre en œuvre de nouvelles méthodes de travail afin d'améliorer la productivité et/ou la prédictivité, au niveau du stade "pool stable" et des clones, sans compromettre la conformité réglementaire de la plateforme CLD.
Pour cela, de nouvelles approches apportant une valeur ajoutée substantielle en termes de productivité, telles que de nouveaux éléments génétiques, de nouveaux milieux/suppléments nutritifs, ainsi que de prédictivité, telles que de nouveaux procédés ou technologies de fed-batch et de simulation de perfusion, seront évaluées. Ce futur poste devra démontrer que la plateforme CLD J.CHO actuelle constitue une solution autonome pour le développement de lignées cellulaires bispécifiques en réalisant une étude de cas et un diaporama sur le développement de lignées cellulaires bispécifiques.
Cette alternance n'attend que vous si :
Vous souhaitez également être un acteur clé dans la mise en œuvre du Système Qualité CLD pour bien faire du premier coup, notamment en définissant 1/ comment gérer les échantillons les plus critiques (amorces, sondes, plasmides), 2/ la liste des tests avec le grade de qualité approprié aux activités de Cell Line Development, et 3/ les SOP et instructions de travail liées à ces activités.
FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.
ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.
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