Scientist 1(Expression)

We are currently recruiting for an experienced Scientist I (Expression) to join our Protein Sciences Team.

Job Title: Scientist I (Expression)

Job Type: Permanent

Location:Alderley Park, Macclesfield, SK10 4TG

Our Company

Evotec is a leader in the discovery and development of novel small molecule drugs with operational sites in Europe and the US. The Company has built substantial drug discovery expertise and an industrialised platform that can drive new innovative small molecule compounds into the clinic. In addition, Evotec has built a deep internal knowledge base in the treatment of diseases related to neuroscience, pain, oncology, inflammation and metabolic diseases. Leveraging these skills and expertise the Company intends to develop best-in-class differentiated therapeutics and deliver superior science-driven discovery alliances with pharmaceutical and biotechnology companies

Purpose of the Role  

Responsible execution of work plans for their protein science area.  Accountable for delivery from early drug discovery workflows in their area of expertise.

Key Accountabilities

• Execution of approved work plans in early drug discovery projects. 
• Provide recommendations for improving Workplans for review and approved by Grade 5 or above  
• Responsible for supporting more than one project across modalities and therapeutic areas
• Will be expected to deliver timely, accurate results of pre-agreed quality to project specifications.
• May conduct some data analysis ahead of internal review prior to release to internal or external customers.

Knowledge & Experience

• Technical knowledge of Protein Biochemistry, Structural Biology or Biophysics with a proven ability to deliver results across target families within agreed timelines and budget, meeting agreed quality criteria.
• Design, clone, and optimise expression constructs for recombinant protein production in E. coli, insect (Baculovirus and S2), and mammalian systems.
• Execute small‑ to large‑scale expression experiments to maximise yield, solubility, and functionality.
• Assess quality via SDS‑PAGE, Western blot, and related analytics.
• Troubleshoot complex expression challenges with creative, data‑driven solutions.
• Understanding of scientific and technical background of experiments.
• Experience of precise execution of workplans.
• Expected to have some independence,  making day-to-day technical decisions
• Expected to follow training provided on the correct use and maintenance of lab. equipment  

 Education and Qualifications

• PhD or a Degree with corresponding experience in a relevant scientific discipline ideally with relevant experience within industry.

Evotec Leadership Competencies

Limited Research: Relies on readily available information and is encouraged to explore more thorough research and analysis

Reactive Approach: Addresses challenges as they arise; in the process of learning to anticipate potential issues; working towards a more proactive approach

Some Initiative: Shows a willingness to learn about driving outcomes but often benefits from guidance and support

Reactive Service: Responds to customer issues when prompted, rather providing short-term solutions

Developing Information Sharing: Occasionally shares information when prompted; learning the importance of open communication

Emerging Team Engagement: Shows some effort in engaging with team members, working on giving interactions more depth

Reactive Problem-Solving: Reliably addresses issues as they arise, starting to learn the importance of proactive planning and anticipation

Benefits Package

• Pension on completion (but not subject to) of your 3-month probationary period. Contributions 5% for employees (salary sacrifice) and 5% for the employer. The employee can opt to increase their contribution, and the employer will match the increase up to a maximum of 7.5%.
• 25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days
• Private health insurance with BUPA for the employee and their partner/family under the company scheme
• Well being support 24/7 and counselling services
• Permanent health insurance provides 75% of the base salary after the qualifying period
• Private dental cover, on completion (but not subject to) of your 3-month probationary period
• Eligibility to participate in the Company Bonus Scheme.  This is a discretionary benefit.
• Career progression within the company, we have excellent training and support and continuing professional development opportunities
• Cycle-to-work scheme
• Refer a friend scheme, team and annual events, recognition awards and many more!

Onsite Facilities

• The company pays for secure onsite parking
• Gym and workout studio, running, walking, and cycling routes
• Good public transport links with the shuttle bus service.

FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.

ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.