Scientist I

Scientist – Drug Metabolism

We are recruiting dedicated scientists for Associate Scientist and Scientist roles to join our Drug Metabolism team based at Alderley Park.

Role: Scientist or Associate Scientist based on experience- Drug Metabolism (ADME),

Role Type: 6 month Fixed term opportunities

Hours: Full time, 37.5 hours per week

Salary: We offer a competitive salary based on skills and experience, with an excellent benefits package

Location:Alderley Park, Macclesfield, SK10 4TG.

Our company

Cyprotex vision is to be pioneers of innovative ADME-Tox partnerships, driving delivery of safer and more effective medicines.  With state-of-the-art facilities and technical expertise, we specialise in in vitro and in silico ADME-Tox services, providing a wide range of assays tailored to our client’s needs.  This includes in vitro ADME screening to support discovery projects, regulatory in vitro ADME and DDI studies to support preclinical and clinical development, specialist mechanistic in vitro human and animal toxicity models and PBPK/QSAR modelling expertise.  As well as supporting clients directly, we have a strong focus on R&D.

Our Alderley Park site is set in the heart of Cheshire surrounded by stunning 400-acre estate, open green spaces, sweeping viewpoints, all within easy reach of Merseyside and Greater Manchester, Staffordshire, and Shropshire. Easy access to public transport.  

As a result of success within the company and future focus on business growth, an exciting opportunity has arisen to be a part of our Drug Metabolism team.  We are responsible for delivering high quality drug metabolism, enzyme inhibition and enzyme induction data to our clients, supporting projects from early discovery right through to clinical development. 

Role

As a Scientist you will be primarily laboratory-based, working with our highly skilled team to ensure that drug metabolism assays, both commercial and R&D focused, are performed to a high standard and within scheduled time-frames.  In addition, you will support the management of drug metabolism assay, training and development of others in the team, and improve the team’s knowledge and processes.

Key Responsibilities

• Conducts routine assays (both manually and using liquid-handling robots) and data processing to high quality within specified time frames. to tight deadlines.
• Demonstrates ability to use scientific knowledge in data analysis, interpretation and troubleshooting.
• Responsibility for assay management; takes ownership for the planning and delivery of specific assay in the group.  Effectively communicates within team and to study managers.  Responsibility for training others and delivering feedback to support development.  Supports senior team with ensuring quality documentation and processes are maintained.
• Proactively and continually identifies improvement opportunities within the group’s processes and assays.  Supports senior scientists in the team to review and action any appropriate improvements.
• Supports senior team members with assay development, validation and bespoke assays, driving forward any projects involved in, working closely with the Information Systems teams where required.
• Coaches and mentors associate scientists and other colleagues within the team on assay execution and data analysis.
• Follows safety regulations and quality control procedures.
• Monitors and maintains stock consumables, communicating with internal buyers and external suppliers.

Skills & Competencies we look for 

• Able to organise daily tasks, to work under pressure and to meet tight deadlines.
• Able to manage multiple activities with awareness of personal and broader team and company priorities to achieve tight deadlines. 
• Ability to organise and prioritise work effectively, including assay scheduling and clear coordination of related communications across the team.
• Able to deliver and ask for feedback, and acknowledge and act on this.
• Able to use initiative to solve problems and troubleshoot with the assistance of other members of the team
• Able to build strong relations within the team, and emerging engagement and collaboration with other key stakeholders.Highly self-motivated and personable.·       
• Possess excellent attention to detail, performing work to an exceptionally high standard, and within company and statutory safety regulations, with good verbal and written communication skills.

Education, Qualifications and Experience

• MSc or BSc degree or equivalent with experience working within a laboratory environment. Experience could be from within a Pharmaceutical company, Biotech, CRO or academia.
• Direct experience in in vitro drug metabolism/drug-drug interaction assays is required.  Knowledge of general laboratory processes is essential alongside experience in the following: liquid handling robotics (such as Tecan EVO® platform), LC-MS/MS or LC-ToF-MS analysis and subsequent data analysis.  

What we can offer you in return

• We offer a competitive salary and benefits package
• Pension on completion (but not subject to) of your 3-month probationary period. Contributions 5% for employees (salary sacrifice) and 5% for the employer. The employee can opt to increase their contribution, and the employer will match the increase up to a maximum of 7.5%.
• 25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days
• Private health insurance with BUPA for the employee and their partner/family under the company scheme
• Wellbeing support 24/7 and counselling services
• Permanent health insurance provides 75% of the base salary after the qualifying period
• Private dental cover, on completion (but not subject to) of your 3-month probationary period
• Eligibility to participate in the Company Bonus Scheme.  This is a discretionary benefit.
• Career progression within the company, we have excellent training and support and continuing professional development opportunities
• Cycle-to-work scheme
• Refer a friend scheme, team and annual events, recognition awards and many more!

Onsite Facilities

• The company pays for secure onsite parking
• Restaurant, Café, and Gastro pub
• Gym and workout studio, running, walking, and cycling routes
• Good public transport links with the shuttle bus service. 

If you are interested in this position please apply uploading your most up to date CV & cover letter

FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.

ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.